![]() ![]() Within its first few years it recruited and genotyped tens of thousands of participants. ![]() In 1996, funded by $12 million in American venture capital, deCODE set up a laboratory and began operations. Iceland, Stefansson's native country, with 270,000 people at the time, fit this description better than any other. In short, this required a population, with people willing to take part in research, a modern healthcare system with meaningful numbers of cases of most common diseases, and much genealogical data. ![]() As a discovery venture in uncharted territory, the strategy was to assemble and query as much data as possible: DNA contributed by tens of thousands of people both broad and deep medical and health data and, crucially, comprehensive genealogies linking all these participants together. A decade before the term was in common use, deCODE's premise was that this was a big data problem: finding variants impacting risk in dynamic interaction with lifestyle and other factors would require studies not at the family level, but at the scale of public health. Stefansson was convinced that these existed and could be identified, but only by working at industrial scale. Yet it was far from universally accepted that there was any significant genetic component to common/complex diseases like heart disease or type 2 diabetes with well-known behavioral and environmental risk factors nor, even if there were, whether such variations could be found given the rudimentary technology for reading DNA. At the time, the causes of some rare diseases - often variations in single genes that could be found by studying small families - were beginning to be uncovered. In 1996, when Stefansson left a tenured position at Harvard Medical School to return to Iceland to found a genomics enterprise, nearly everything in his thinking was unproven or controversial. This example has helped to spur investment in genomics and precision therapeutics by other pharmaceutical and biotechnology companies. Since 2012, it has been an independent subsidiary of Amgen and its capabilities and discoveries have been used directly in the discovery and development of novel drugs. But it has also made pioneering contributions to the realization of precision medicine more broadly, through public engagement in large-scale scientific research the development of DNA-based disease risk testing for individuals and across health systems and new models of private sector participation and partnership in basic science and public health. deCODE is probably best known for its discoveries in human genetics, published in major scientific journals and widely reported in the international media. The company was founded in 1996 by Kári Stefánsson with the aim of using population genetics studies to identify variations in the human genome associated with common diseases, and to apply these discoveries "to develop novel methods to identify, treat and prevent diseases." Īs of 2019, more than two-thirds of the adult population of Iceland was participating in the company's research efforts, and this "population approach" serves as a model for large-scale precision medicine and national genome projects around the world. DeCODE genetics ( Icelandic: Íslensk erfðagreining) is a biopharmaceutical company based in Reykjavík, Iceland. ![]()
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![]() Illustrating improvement each offseason in an area where it was much needed. In 2017, they became a turnover-happy group and brought in 31 turnover gains combined (fumble and interceptions), an improvement from the 19 they racked up in 2016. The first season, the Hurricanes were a sack-happy group, improving to 37 sacks in 2016 from 26 sacks in the course of the 2015 season. Let’s give props to Miami’s defensive staff who have improved the unit in some form or fashion since their arrival three seasons ago. So what does that mean for the defense? How do you improve on a season where you gave the offense numerous possessions, even if they failed to capitalize on said chances? How do they become a better group? What we’re trying to say is that, come 2018, Miami is going to need to rely less on the Turnover Chain chant. A batted pass here, a fumble recovery there, and a ‘johnny on the spot’ interception there easily can turn into incompletions or completions for the offense a year later. If football is a game of inches, then a turnover can be a stat of good fortune. The reason is because turnovers are, for a lack of a better term, random. The numbers are great, and so is the production however, replicating that success on defense will be hard to do, even with much of last season’s unit still intact. The Hurricanes finished the 2017 season tied for third in the nation in the total turnover margin, one behind UCF’s 32 and seven behind Wyoming’s nation-leading 38. ![]() In 2017, the ’Canes turnover gain total jumped to 31 (14 fumbles, 17 interceptions)! For context, Miami has accumulated 20 or more turnovers six times within the last decade, before last season, with the next highest total being 28 in the 2010 season. The season before the birth of the chain, the Hurricanes managed to gain 19 combined turnovers (11 fumbles, 8 interceptions) in 2016. ![]() Yet this article has more to do with the actual turnovers diminishing, rather than the shine of the Cuban links. While former Oakland Raiders’ WR Michael Crabtree may have had his chain snatched-multiple times-and opponents mock snatching the chain, the Hurricanes’ piece of jewelry remains a useful tool in a sport that is chock full of motivational instruments. Many an article and TV segment, and even some clothing apparel, have been spawned by the birth of the magnificent 24 karat accessory. This has more to do with the appearance of the glorious jewelry that flipped the college football world on its head a season ago. Turnover Chain, Turnover Chain, Turnover Chainīefore you go in on the comment section, no this is not another referendum on whether the Turnover Chain should remain or be retired. ![]() ![]() ![]() Glass pad: Tim Holtz Glass Media Mat - Protect your project with a glass pad. One size does not fit all.īestReviews Home Improvement and DIY Expert ![]() Also, you may need different wheels depending on what type of cut you’re making and how thick the glass is. In case your wheel breaks or grows dull, it never hurts to have a couple of spare cutting wheels handy, like the Fletcher Terry Glass Cutting Wheel. Save yourself some time and effort by getting extra oil when you get your glass cutter.Įxtra cutting wheel: Fletcher Terry Glass Cutting Wheel - Have extra cutting wheels on hand so there’s never a dull moment. We like CRL Professional Glass Cutter Oil. The more glass you cut, the more oil you’ll use and, consequently, the more oil you’ll need to replace. Oil: CRL Professional Glass Cutter Oil - Be slick, and stock up on oil. But each manufacturer often only offers one color, so the cutter you prefer may only be available in one color. Glass cutters are available in a variety of colors, from black to green to gold to gray. Tungsten carbide blades are more durable, but steel blades are cheaper. The cutting heads are usually tungsten carbide or hardened steel. Some glass cutters have wooden handles as well. Cutters that aren’t self-oiling normally have aluminum or steel handles covered with rubber for a better grip. Most self-oiling glass cutters have hollow brass handles for the oil tank, but some are plastic. Some glass cutters have heads that can be rotated 360 degrees, allowing you to set the cutting head to the angle that is best for you.īestReviews Home Improvement and DIY Expert Materials No two people hold their glass cutters the same way or at the same angle. Glass workers tap the knocking head gently along a scored piece of glass to facilitate a clean break. This is basically a round metal ball on the back end of some cutters. Some glass cutters include snapping notches of various thicknesses to help break off the glass after you’ve used your cutter to score the glass. Multi-blade glass cutters don’t have self-oiling mechanisms, so you’ll have to manually oil as you work. This is a great feature if you’re constantly changing from one type of glass to another or from one thickness to another. ![]() When you rotate the hexagon, a different cutting blade is presented. Each side of the hexagon blade is actually a cutting surface. Some glass cutters have a six-sided wheel on the tip. Each of these grip styles works well the one you choose depends on personal preference.īestReviews Home Improvement and DIY Expert Features Multi-blade cutting wheel There are also other less-common grip types, such as Toyo’s custom grip and the Thomas grip. A pistol grip cutter has a molded handle in the style of a revolver, which shifts control of the glass cutter from the fingers to the hand. A traditional pencil grip glass cutter is held like a pen or pencil between the thumb and forefinger. There are two main types of glass cutter grips. If you’ve never used this type of glass cutter, you may need to do a few practice cuts to get a feel for applying the proper amount of pressure. However, there’s a bit of a learning curve with pressure-fed glass cutters. Pressure-fed cutters solve the storage mess problems of gravity-fed cutters. To stay safe, top your glass cutter with a pen cap when not in use. Storing them with the sharp end up is a good way to cut yourself next time you reach for them, but it’s the only way to keep the oil from running out and making a mess. Gravity-fed cutters can leak when you’re not using them since they operate on gravity. There are two main types of self-oiling glass cutters: gravity-fed and pressure-fed. When you’re using the cutter, it oils itself. ![]() Unscrew the cap, fill it with oil, and you’re ready to go. There is a small tank in the handle of the cutter. BestReviews Home Improvement and DIY Expert Self oilerĪ self-oiling glass cutter is exactly what it sounds like. ![]() ![]() Toilet paper rolls are something we all have at home, so here’s a great tutorial that won’t cost you much. Plus, look how cute that would look on their desk! DIY Paper Roll Pencil Cups It’s a quick and easy project that you’ll enjoy making with the kids. This is a creative tutorial unlike any you’ve seen! It shows you how to make simple pencil cup out of rulers. Following these five steps you will have a fun filled afternoon and it would also make a great gift for their teacher! DIY Ruler Pencil Holder Putting together a lovely pencil holder is the perfect way to get into that back to school mood. Going back to school can be tough, both for parents and kids… or maybe just the kids lol. Related DIY Post: Desk Organization DIY Tutorials Back To School Kids Pencil Holder Plus, you can easily switch up the pattern or colors to match the aesthetic of your desk or workspace! If you’re looking for some cheap pencil holders that you can make with things you already have… this tutorial is it! They’re made out of tin cans and decorated with simple but modern patterns to give them some pop. If you’re going for that chalk paint, farmhouse vibe, these are going to look amazing on your desk at home! Save this tutorial for your next craft night! DIY Pencil Holder From Empty Tin Cans Mason jars can be the base for a whole variety of crafts because of how easily they can be decorated! Turn them into some cute pencil holders that you and your kids can use once the school year starts. Here are the tutorials I found: Rustic DIY Painted Mason Jars They are easy to download, free… and will keep you and the kids entertained for hours! Check out these free printables that I have been working on. I also love to find fun and new activities to do as a family. Find a style you’re inspired by and let’s get started!ĭIY projects aren’t the only thing that my household loves. ![]() So, make yourself an awesome pencil organizer that will clean up all that clutter on your desktop. Let’s get in the mood for crafting with some of the best DIY pencil holders I could find! We all love a nice clean and organized workspace or play area, right?! And there’s nothing better than making something that you’ll use daily. ![]() ![]() ![]() The archetype relies on equipping the "Noble Knights" with the "Noble Arms" Spell Cards and take advantage of this, either by searching for more support or simply destroying cards. Sir Agravain, Sir Gaheris, and Sir GarethĬarolingian legends Knights Infernoble Knight Origin Arthurian legends Knights Noble Knight French chevaleresse, Spanish caballera, German Ritterin) of the words for "knight" do occur to some degree, however in this case, they aren't used, to reduce ambiguity and prevent grammatical gender from interfering with the game play. " Noble Knight Joan", despite being female, is referred to as a male in all non-English TCG.However, cards whose names contain feminine and plural variants of archetype names seem to be implicitly considered for membership as with other archetypes. This makes support confusing for a few "Noble Knight" support cards, such as "Noble Knight Brothers", " Ignoble Knight of High Laundsallyn" and "Artorigus, King of the Noble Knights". In Italian, agreement is still applied on "Noble Knight Brothers", "Last Chapter of the Noble Knights" and "Noble Knights of the Round Table", with the plural form being "Nobili Cavalieri".An ungrammatical plural form is used in Portuguese ("Nobre Cavaleiros"), without making the adjective "Nobre" agree, as shown on "Last Chapter of the Noble Knights" and "Noble Knights of the Round Table".Plural forms are never used in French, German and Spanish card names, as shown on " Artorigus, King of the Noble Knights", " Noble Knight Brothers", " Last Chapter of the Noble Knights" and " Noble Knights of the Round Table".However, in other languages there is, which makes the naming of the archetype potentially complicated. There is no agreement on the noun phrase "Noble Knight" in English (the plural form is simply "Noble Knights", with no change reflected on the adjective "Noble").In French, the adjective is placed after the noun in both cases of "Noble Knight" ("Chevalier Noble") and "Noble Arms" ("Armes Nobles"), as "Ignoble Knight" cards are simply named "Chevalier Noble Infâme" (literally "Infamous Noble Knight"). This is to make sure that the support cards work well with "Ignoble Knight" cards which are called "Ignobile Cavaliere", "Inobre Cavaleiro" and "Innoble Caballero" however, in these languages the " Noble Arms" archetype has the adjective after the noun meaning "Arms". In Italian, Portuguese and Spanish, the archetype names are respectively "Nobile Cavaliere", "Nobre Cavaleiro" and "Noble Caballero", with the adjective meaning "Noble" coming before the noun meaning "Knight".Continued abuse of our services will cause your IP address to be blocked indefinitely. 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Overusing our search engine with a very large number of searches in a very short amount of time. ![]() Using a badly configured (or badly written) browser add-on for blocking content.Running a "scraper" or "downloader" program that either does not identify itself or uses fake headers to elude detection.Using a script or add-on that scans GameFAQs for box and screen images (such as an emulator front-end), while overloading our search engine.There is no official GameFAQs app, and we do not support nor have any contact with the makers of these unofficial apps. Continued use of these apps may cause your IP to be blocked indefinitely. This triggers our anti-spambot measures, which are designed to stop automated systems from flooding the site with traffic. 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The latest version of the Opera browser sends multiple invalid requests to our servers for every page you visit.The most common causes of this issue are: Your IP address has been temporarily blocked due to a large number of HTTP requests. ![]() ![]() Giant shadows that seemed to move by themselves due to movement of the cloud layer (this movement is another part of the definition of the Brocken spectre), and that were surrounded by glories, may have contributed to the reputation the Harz mountains hold as a refuge for witches and evil spirits. Because the peak is above the cloud level and the area is frequently misty, conditions conducive to casting a shadow on a cloud layer are common. The name derives from the Brocken, the tallest peak of the Harz mountain range in Germany. When viewed from a mountain or tall building, glories are often seen in association with a Brocken spectre, also called Mountain spectre, the apparently enormously magnified shadow of an observer, cast (when the sun is low) on clouds below the mountain on which the viewer is standing. Main article: Brocken spectre A solar glory and Brocken spectre This is sometimes called The Glory of the Pilot. In the latter case, if the plane is flying sufficiently low for its shadow to be visible on the clouds, the glory always surrounds it. Outdoor glories are commonly observed from aircraft. Because this point is diametrically opposite to the sun's (or moon's) position in the sky, it usually lies below the observer's horizon except at sun (or moon) rise and set. Like a rainbow, outdoor glories are centred on the antisolar (or, in case of the moon, antilunar) point, which coincides with the shadow of the observer's head. "Glories can be seen on mountains and hillsides, from aircraft and in sea fog and even indoors." In the right conditions, a glory and a rainbow can occur simultaneously. The angular size of the inner and brightest ring is much smaller than that of a rainbow, about 5° to 20°, depending on the size of the droplets. The rings are rarely complete, being interrupted by the shadow of the viewer. Glories arise due to wave interference of light internally refracted within small droplets.ĭepending on circumstances (such as the uniformity of droplet size in the clouds), one or more of the glory's rings can be visible. Due to its appearance, the phenomenon is sometimes mistaken for a circular rainbow, but the latter has a much larger diameter and is caused by different physical processes. ![]() The glory consists of one or more concentric, successively dimmer rings, each of which is red on the outside and bluish towards the centre. The position of the glory's centre shows that the observer was in front of the wings.Ī glory is an optical phenomenon, resembling an iconic saint's halo around the shadow of the observer's head, caused by sunlight or (more rarely) moonlight interacting with the tiny water droplets that comprise mist or clouds. Optical phenomenon that resembles an iconic saint's halo about the shadow of the observer's head ![]() ![]() ![]() 6 biggest movie ever, topping 'Spider-Man: No Way Home.' Its close to surpassing the box-office totals of 'Avengers: Infinity War' and 'Star Wars. PG-13 for intense sequences of sci-fi violence and action throughout, language and some crude references. 'Avatar: The Way of Water' is now the No. 'Top Gun: Maverick' just passed 'Avengers: Infinity War' at the all-time domestic box officethese are the 10 highest grossing movies ever Published Mon, 12:01 PM EDT Updated Thu, Aug. July 31st, 2018 by Walt Disney Home Entertainment But what are the actor's biggest films so far Box Office Mojo has them listed. ![]() See the Box Office tab (Domestic) and International tab (International and Worldwide) for more Cumulative Box Office Records.Īmazon VOD (Bonus Content), Amazon VOD, Amazon VOD, Amazon VOD (With Bonus Content), Amazon VOD, Amazon VOD (Bonus Content), Amazon 4K UHD VOD That said, even though Infinity War made a staggering 2 billion dollars worldwide, according to Box Office Mojo, was it still worth that hefty 500 million (Or, 321 million). Movie Lists Chris Hemsworth's 10 Highest-Grossing Movies, According To Box Office Mojo By Saim Cheeda Published Chris Hemsworth will taste success again with Thor: Love and Thunder. All Time Domestic Box Office for Super Hero MoviesĪll Time International Box Office for Super Hero MoviesĪll Time Worldwide Box Office for Super Hero MoviesĪll Time Domestic Box Office for Walt Disney MoviesĪll Time International Box Office for Walt Disney MoviesĪll Time Worldwide Box Office for Walt Disney Movies Film News 9:33am PT ‘Avatar 2’ Passes ‘Avengers: Infinity War’ as Fifth-Biggest Movie Ever With 2.05 Billion By Brent Lang, Jordan Moreau Walt Disney Co./Courtesy Everett. Updated: 4:51 pm Posted: 10:38 pm Top Gun: Maverick has crossed another impressive milestone during its theatrical run as it has now officially passed Avengers: Infinity. ![]() ![]() ![]() ![]() In 2022, Natasha was included on the charity album “Stars of Classical Crossover: Christmas” in benefit of the Wallace & Gromit Children’s Charity. The Gala Tour features a classical crossover repertoire. During the covid-19 pandemic, she created an online concert series for the magazine that has seen her perform in the same line-up as Alex Sharpe, Lucy Kay, Barbara Padilla, Classical Reflection, and more on the virtual stage. Gala - An Evening With Sarah Brightman was a 2016-17 concert tour by British soprano singer Sarah Brightman with eleven shows in Japan, three in South Korea and three in Mexico. Natasha is the creator and editor of ‘Classical Crossover Magazine’ a venture that has allowed her to interview many of the top stars in the genre including Sarah Brightman, Celtic Woman, Mirusia, Paul Potts, and more. Brightman (sarahbrightmanmusic): 'sarahbrightman sarahbrightmanmusic firstofmay christmassongs beegees christmas classic vienna. Sarah Brightmans soprano voice has sold millions of records and been heard in arenas, cathedrals, and Olympic stadiums around the world. In 2021, she was nominated for the ‘Future Classic Women Awards’ show on Men’s & Women’s Radio Station. Natasha has released a series of Holiday singles “A Place Called Home” (2020), “One Little Boy,” and “The Perfect Year” (2021). ![]() Natasha graduated in 2012 with a Bachelor’s of Music. At 20, she was a winner of the 2011 Young Artist Competition at Andrews University. ,Japan,Music DVD, (DVD) / The worlds greatest diva, Sarah Brightmans first Christmas. At age 18, Natasha made her opera debut playing the part of the mother in Menotti’s ‘Amahl and the Night Visitors’ with the Eastern Festival Opera. CHRISTMAS SYMPHONY (DVD) (DVD) by SARAH BRIGHTMAN is in stock now. Explore songs, recommendations, and other album details for Christmas In Vienna V by Plácido Domingo, Sarah Brightman, Helmut Lotti, Riccardo Cocciante, Gumpoldskirchner Spatzen, Wiener Symphoniker, Steven Mercurio. For Natasha music has always been closely tied to her faith. ![]() ![]() ![]() The Albacore tuna ( Thunnus alalunga ), also known as white tuna, is the most prized of its kind for its texture and flavor. Bonito Del Norte Tuna from Ortiz is the true premium quality white tuna it is imported from Spain they has light pink color, mild flavor and firm consistency. There deep respect and love for the sea leads them to firmly believe in traditional fishing methods. In the case of the Bonito del Norte, the best coastal season is from July to October. It is known as coastal when a fish is in the best conditions of size and flavor to be caught. The result can be seen in the exquisite flavor and unmistakable texture of their products that make the difference. And there careful handling of the fish they use yields a product distinguished by its high quality. At Conservas Ortiz they have great respect for tradition, coastal fishing based on the tides, and the exclusive purchase of north coast spain’s tuna which are line-caught, one-by-one. The fifth generation of the same family manages the company today. ![]() In 1942, José Ortiz and his son, José Antonio Ortiz, created the limited company which would later become Conservas Ortiz S.A. Anchovies were the star product of Ortiz. ![]() Ortiz have been hand preparing their tuna since 1891. At the beginning of the 20th century, Conservas Ortiz began to make its mark worldwide. “Since the beginning, their history has been linked to traditional fishing and respect for the sea. Ingredients: White Tuna, Olive Oil, Salt.We recommend it with a green salad of lettuce or just inside a sandwich with sliced of tomatoes. 130 years filling your table with flavor, so that you can continue discovering new ways to take care of yourself everyday.They are Cooked and packed in olive oil which helps the tuna retain its moisture, giving it a succulent, tender texture. They are caught using environmentally friendly traditional methods. Ortiz Bonito tuna is a pale color and has a delicate flavor that is at its best when eaten simply.Tunas are a genuine, nutritious food rich in noble proteins and in vitamins P, B and A, minerals, and unsaturated fatty acids – perfect for a balanced diet!.A whim that, fortunately, we can enjoy daily. Obviously there is nothing written about tastes, but if there is a desired fish above all others, it is the Bonito del Norte. The Bonito del Norte has always been considered an exquisite product. Behind the success of the “King of tuna” are its smooth, delicate and slightly fibrous texture, and its unique flavor, which makes each bite a pleasure.It may not be reproduced in any way whatsoever without Ocado Limited's prior consent, nor without due acknowledgement. This data is supplied for personal use only. You should also note that the picture images show only our serving suggestions of how to prepare your food - all table accessories and additional items and/or ingredients pictured with the product you are purchasing are not included. Where this description contains a link to another party's website for further information on the product, please note that Ocado has no control over and no liability for the contents of that website. Ocado is therefore unable to accept liability for any incorrect information. If you do require precise ingredient information you should consult the manufacturer, whose contact details will appear on the packaging or label. You should note that products and their ingredients are subject to change. While we have taken care in preparing this summary and believe it is accurate, it is not a substitute for your reading the product packaging and label prior to use. This page serves as a summary for information purposes only, and are designed to enhance your shopping experience on the Ocado website. ![]() ![]() ![]() I do know that sometimes the additional lists can be helpful for students learning English. While many children working beyond the 3rd or 4th Fry list will not be completing Fry Word checks, I wanted to provide a full set. The checklists I have created have all 1,000 Fry Words. I never wanted to end an assessment with a child feeling like they were not capable I might write the word red in a red marker or the child’s name. In cases when I was working with a second grader who couldn’t read Fry Words 1 – 10, I would try to take a moment to find a few words that the child could read. If a child is still struggling, I try to get through the first column on the list as my starting point. Instead of pushing through the list, I will pull out the 1st word list. If you are working with a second grader who can’t read the first 10 words on the 2nd word list, imagine how they are going to feel struggling through all 100 words. I always felt like this could really crush a child’s confidence. Some teachers feel that is important to have a child attempt every word on the list you are checking. You do not want a sight word check to become a point of frustration for any child. While it might be important that you are checking sight word mastery in order to gather data and then be able to document growth. In 2nd grade, many will begin by checking the second 200 words. In first grade, many will begin by checking the first 100 words. You might decide to test just this child for your own documentation. It is possible you have a child who is already reading and you are curious how many words they know. ![]() Instead, they might do a check on letter and number ID. ![]() Many kindergarten teachers will not begin the year by checking sight word mastery. Now that you know all these sight words, it's great to actually use them with your child or students! I've written several sight word games to give kids fun practice in recognizing these all-important words at an early age.First, it is important to know the general breakdown for which sight words should be mastered in each grade level: Kindergarten Sight Wordsįor most students, you would begin assessing children on the word list you would like them to master by the end of the year. Tenth Hundred Words Tips for Using Sight Word Lists Second Hundred (Words 101 - 200) - Printable List ListĤ over say set try new great put kind sound where end hand take help does picture only through another again little much well change work before large off know line must play place right big spell years too even air live means such away me old because animal back any turn house give same here point most tell why page very boy ask letter after follow went mother things came men answer our want read found just show need study name also land still good around different learn sentence form home should man three us America think small move worldĤ high saw important miss every left until idea near don't children enough add few side eat food while feet face between along car watch own might mile far below close night Indian country something walk real plant seem white almost last next sea let school hard began above father open grow girl keep example took sometimes tree begin river mountains never life four cut start always carry young city those state talk earth both once soon eyes paper book list light together hear song thought got stop being head group without leave under often second family story run late it's Find Another Sight Word List: 4 the or will number of one up no and had other way a by about could to words out people in but many my is not then than you what them first that all these water it were so been he we some called was when her who for your would am on can make its are said like now as there him find with use into long his an time down they each has day I which look did at she two get be do more come this how write made have their go may from if see partįor the first 100 words. ![]() |
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